gene 526 words KG: PRDX1 2026-03-21
kind:genesection:genesstate:published
Contents

PRDX1 Gene

🧬 Gene Info
Gene SymbolPRDX1
Full NamePeroxiredoxin 1
Chromosome1p34.2
FunctionPeroxiredoxin 1 is a ubiquitous antioxidant enzyme
Molecular Weight22 kDa
Amino Acids199 aa
PathwaysGLYCOLYSIS
UniProt IDQ06830
NCBI Gene ID8852
Ensembl IDENSG00000117450
OMIM176583
GeneCardsPRDX1
Human Protein AtlasPRDX1
ApproachMechanism
OverexpressionGene therapy
Associated DiseasesLymphoma, Tumor
Known Drugs/CompoundsLipopolysaccharide, LPS
InteractionsERK1, TRAF6, CHUK, PRDX6, MAPK14, BECN1
KG Connections177 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (4)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.56
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Nucleolar Stress Response Normalization
Score: 0.38

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Packard Center for ALS Research
institution · KG edge: activates
IL1B Gene - Interleukin 1 Beta
gene · KG edge: activates
IKBKB Gene
gene · KG edge: activates
GPX4 Gene - Glutathione Peroxidase 4
gene · KG edge: activates
ERK1 (MAPK3) — Extracellular Signal-Regulated Kinase 1
gene · KG edge: activates

Knowledge Graph (12 edges)

PRDX1 regulates HYDROGEN_PEROXIDE
PRDX1 regulates ERK1
PRDX1 regulates ERK2
PRDX1 regulates H3S28
PRDX1 regulates IL6
PRDX1 activates ERK1
PRDX1 activates TRAF6
PRDX1 activates CHUK
PRDX1 activates PRDX6
PRDX1 activates MAPK14