gene 2,465 words KG: TPM3
Contents

TPM3 Gene

🧬 Gene Info
Gene SymbolTPM3
Full NameTropomyosin 3
Chromosome1p36.22
Molecular Weight33 kDa
Amino Acids248 aa
Exons9
UniProt ID[P06753](https://www.uniprot.org/uniprot/P06753)
Ensembl IDENSG00000143548
GeneCardsTPM3
Human Protein AtlasTPM3
Chromosomal location1p36.22
Genomic size~11 kb
Exon count9 exons
Protein248 amino acids, ~33 kDa
TPM3.1 (γ-tropomyosin)Muscle-specific isoform
Associated DiseasesAls, Cancer, Prostate Cancer
InteractionsARHGEF2, Fus, IRF2BP2, LMNA, NPM1, PRDX1
KG Connections53 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (8)

CYP46A1 Overexpression Gene Therapy
Score: 0.77
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Reelin-Mediated Cytoskeletal Stabilization Protocol
Score: 0.69
Cross-Seeding Prevention Strategy
Score: 0.69
Nucleolar Stress Response Normalization
Score: 0.65
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Cryptic Exon Silencing Restoration
Score: 0.53
RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (10)

ARHGEF2 Gene
gene · KG edge: interacts_with
CASP1 Gene
gene · KG edge: expressed_in
CD44 - Cell Surface Glycoprotein
gene · KG edge: expressed_in
CXCR4 Gene
gene · KG edge: expressed_in
LMNA Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

CD44 expressed_in TPM3
CASP1 expressed_in TPM3
MYD88 expressed_in TPM3
TPM3 expressed_in TNF
TPM3 expressed_in RIPK1
TPM3 expressed_in TNFRSF1A
TPM3 expressed_in CXCR4
ARHGEF2 associated_with TPM3
LMNA associated_with TPM3
NPM1 associated_with TPM3

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