gene 2,465 words KG: TPM3 2026-03-27
kind:genesection:genesstate:published
Contents

TPM3 Gene

🧬 Gene Info
Gene SymbolTPM3
Full NameTropomyosin 3
Chromosome1p36.22
Molecular Weight33 kDa
Amino Acids248 aa
Exons9
UniProt ID[P06753](https://www.uniprot.org/uniprot/P06753)
Ensembl IDENSG00000143548
GeneCardsTPM3
Human Protein AtlasTPM3
Chromosomal location1p36.22
Genomic size~11 kb
Exon count9 exons
Protein248 amino acids, ~33 kDa
TPM3.1 (γ-tropomyosin)Muscle-specific isoform
Associated DiseasesAls, Cancer, Prostate Cancer
InteractionsNPM1, LMNA, ARHGEF2, SQSTM1, PRDX1, AND
KG Connections54 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (8)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Cryptic Exon Silencing Restoration
Score: 0.46
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Cross-Seeding Prevention Strategy
Score: 0.45
Reelin-Mediated Cytoskeletal Stabilization Protocol
Score: 0.45

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (10)

Packard Center for ALS Research
institution · KG edge: associated_with
SQSTM1 — Sequestosome 1 (p62)
gene · KG edge: associated_with
PRDX1 Gene
gene · KG edge: associated_with
NPM1 Gene
gene · KG edge: interacts_with
MYD88 Gene
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

TPM3 expressed_in TNF
TPM3 expressed_in RIPK1
TPM3 expressed_in TNFRSF1A
TPM3 expressed_in CXCR4
TPM3 interacts_with NPM1
TPM3 interacts_with LMNA
TPM3 associated_with PRDX1
TPM3 interacts_with ARHGEF2
TPM3 interacts_with SQSTM1
TPM3 interacts_with PRDX1