gene 507 words KG: CAMKK2 2026-03-12
kind:genesection:genesstate:published
Contents

CAMKK2 Gene

🧬 Gene Info
Gene SymbolCAMKK2
Full NameCalcium/Calmodulin-Dependent Protein Kinase Kinase 2
Chromosome12q24.13
Protein TypeKinase
FunctionCAMKK2 is a serine/threonine protein kinase
Molecular Weight65 kDa
PathwaysAMPK, AMPK Signaling, ampk, mTOR
UniProt IDQ96HS5
NCBI Gene ID8146
Ensembl IDENSG00000110939
OMIM615092
GeneCardsCAMKK2
Human Protein AtlasCAMKK2
Associated DiseasesAging, Alzheimer, Diabetes, Ferroptosis, dementia
InteractionsLC3, COX4I1, GFAP, IBA1, LAMP2, MAP1LC3B
KG Connections80 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.66
AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.59
Blood-Brain Barrier SPM Shuttle System
Score: 0.56
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Piezoelectric Nanochannel BBB Disruption
Score: 0.41

Related Analyses (4)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (10)

Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: associated_with
Packard Center for ALS Research
institution · KG edge: activates
Autoimmune Hypothesis in Alzheimer's Disease
hypothesis · KG edge: expressed_in
CTSB Gene
gene · KG edge: associated_with
CDKN1A — Cyclin-Dependent Kinase Inhibitor 1A
gene · KG edge: associated_with

Knowledge Graph (12 edges)

CAMKK2 expressed_in P2RX7
CAMKK2 expressed_in P2RX4
CAMKK2 inhibits LC3
CAMKK2 associated_with CDKN1A
CAMKK2 associated_with CTSB
CAMKK2 associated_with ARNTL
CAMKK2 co_expressed_with OCLN
CAMKK2 activates COX4I1
CAMKK2 activates GFAP
CAMKK2 activates IBA1