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gene 1,022 words KG: BMI1
Contents

BMI1

🧬 Gene Info
Gene SymbolBMI1
Full NameBMI1 Proto-Oncogene, Polycomb Ring Finger
Chromosome10p12.2
Functionencodes a core component of the Polycomb Repressive Complex 1 (PRC1).
PathwaysEpigenetic
UniProt IDP35226
Ensembl IDENSG00000168283
OMIM164831
GeneCardsBMI1
Human Protein AtlasBMI1
Associated Diseasesneurodegeneration
InteractionsAPOPTOSIS, DNA
KG Connections33 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73Palmitoylation-Targeted BACE1 Trafficking Disruptors
Score: 0.69Metabolic Switch Targeting for A1→A2 Repolarization
Score: 0.73Metabolic Reprogramming via Microglial Glycolysis Inhibition
Score: 0.67FOXO3-Longevity Pathway Epigenetic Reprogramming
Score: 0.63

Related Analyses (4)

Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completedSynaptic pruning by microglia in early AD
neurodegeneration · archivedEpigenetic reprogramming in aging neurons
neurodegeneration · archivedCircuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (5)

cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40Epigenetic Dysregulation Validation in Parkinson's Disease
clinical · proposed · Score: 0.40AAV-LRRK2 Gene Therapy IND-Enabling Study Design
clinical · proposed · Score: 0.40Microglial Aging and Immune Memory in Neurodegeneration — Tr
validation · proposed · Score: 0.40Non-Motor Symptom Progression in Parkinson's Disease — Mecha
clinical · proposed · Score: 0.40

See Also (7)

Amyotrophic Lateral Sclerosis
redirect · KG edge: activatesApoptosis in Neurodegeneration
entity · KG edge: inhibitsDNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: inhibitsEpigenetic Clocks in Neurodegeneration — Causal Drivers
experiment · KG edge: regulatesCEBPB Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

FOS regulates BMI1
HK2 therapeutic_target BMI1
LGALS3 regulates BMI1
RELA regulates BMI1
SOD2 regulates BMI1
FGF21 regulates BMI1
DUSP6 regulates BMI1
BMI1 regulates CEBPB
PTEN therapeutic_target BMI1
BMI1 activates Cancer

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