gene 1,693 words KG: CDKN1B 2026-03-26
kind:genesection:genesstate:publishedCDKN1Bp27Kip1cell cyclecyclin-dependent kinase inhibitorneurogenesisneurodegeneration
Contents

CDKN1B — Cyclin-Dependent Kinase Inhibitor 1B

🧬 Gene Info
Gene SymbolCDKN1B
Full NameCyclin-Dependent Kinase Inhibitor 1B
Aliasesp27/Kip1
Protein TypeKinase
Functionis a member of the CIP/KIP family of cyclin-dependent kinase (CDK) inhibitors.
Amino Acids198 aa
Ensembl IDENSG00000100994
GeneCardsCDKN1B
Human Protein AtlasCDKN1B
Apoptosis regulationInteraction with ASK1 and modulation of JNK signaling
Associated DiseasesLupus
InteractionsCTNNB1, CXCR4, HMGB1, IGF1, LAMP1, TFRC
KG Connections50 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (4)

Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.51
LRP1-Dependent Tau Uptake Disruption
Score: 0.44
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.41

Related Analyses (4)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

LRRK2 G2019S Transgenic Mouse Model
model · KG edge: associated_with
MAPK Signaling Pathways in Neurodegeneration
mechanism · KG edge: therapeutic_target
Adaptive Immunity in Neurodegeneration
mechanism · KG edge: associated_with
MAP1LC3B — LC3B
gene · KG edge: associated_with
MAP1LC3A Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

CDKN1B associated_with ATG7
CDKN1B associated_with RUBCN
CDKN1B associated_with CYBB
CDKN1B associated_with LRRK2
CDKN1B associated_with LC3
CDKN1B associated_with MAP1LC3B
CDKN1B associated_with DRAM1
CDKN1B therapeutic_target CTSB
CDKN1B interacts_with CTNNB1
CDKN1B interacts_with CXCR4