| Gene Symbol | CHUK |
| Full Name | IKK Alpha (IκB Kinase Alpha) |
| Chromosome | 10q24.31 |
| Protein Type | Kinase |
| Function | is a critical serine/threonine protein kinase that plays a central role in the NF-κB signaling pathway. |
| Molecular Weight | 85 kDa |
| Amino Acids | 745 aa |
| Exons | 21 |
| Pathways | NF-κB signaling |
| UniProt ID | [O15111](https://www.uniprot.org/uniprot/O15111) |
| Ensembl ID | ENSG00000028137 |
| OMIM | 600655 |
| GeneCards | CHUK |
| Human Protein Atlas | CHUK |
| Histone H3 | At Ser10, linking NF-κB to chromatin remodeling |
| Associated Diseases | neurodegeneration |
| Interactions | AND, AUTOPHAGY, BECN1, CANCER, DSDNA, ECSIT |
| KG Connections | 93 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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