gene 987 words KG: GAL 2026-03-21
kind:genesection:genesstate:published
Contents

GAL Gene

🧬 Gene Info
Gene SymbolGAL
Chromosome11q13.2
FunctionThe GAL gene encodes preprogalanin, which is processed to galanin (1-29) and galanin message-associated peptide (GMAP).
Amino Acids30 aa
PathwaysApoptosis, Hippo Pathway
Ensembl IDENSG00000178394
GeneCardsGAL
Human Protein AtlasGAL
Associated DiseasesAging, Alzheimer, Cancer, Ms, Rheumatoid Arthritis, Senescence
InteractionsPI3K, NRF2, AKT, TLR4, TREM2, NLRP3
KG Connections290 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (11)

Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67
CYP46A1 Overexpression Gene Therapy
Score: 0.63
APOE-Dependent Autophagy Restoration
Score: 0.61
Circadian Clock-Autophagy Synchronization
Score: 0.55
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.52

Related Analyses (6)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Synaptic pruning by microglia in early AD
neurodegeneration · archived

See Also (13)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: inhibits
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: activates
Alzheimer Indonesia
institution · KG edge: associated_with
BMAL1 (ARNTL) Gene
gene · KG edge: associated_with
ATG13 — Autophagy Related 13
gene · KG edge: activates

Knowledge Graph (12 edges)

GAL activates PI3K
GAL activates NRF2
GAL activates AKT
GAL activates TLR4
GAL activates TREM2
GAL activates NLRP3
GAL regulates TAZ
GAL regulates CLOCK
GAL associated_with BMAL1
GAL regulates ARNT