gene 1,853 words KG: GOT1
Contents

GOT1 Gene

🧬 Gene Info
Gene SymbolGOT1
Full NameGlutamic-Oxaloacetic Transaminase 1
Chromosome10q24.3
Protein TypeEnzyme
FunctionAmino acid metabolism — Interconversion of aspartate and glutamate
Molecular Weight45 kDa
Amino Acids413 aa
Exons11
PathwaysFerroptosis, Proteasome, Ubiquitin-Proteasome
UniProt IDP17174
NCBI Gene ID2805
Ensembl IDENSG00000163283
OMIM138150
GeneCardsGOT1
Human Protein AtlasGOT1
Associated DiseasesCarcinoma, Hepatocellular Carcinoma
InteractionsBECLIN1, ACSL4, TFR1, GPX4, GPT, MAP1LC3B
KG Connections73 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (4)

ACSL4-Driven Ferroptotic Priming in Disease-Associated Micro
Score: 0.83
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65
Blocking AGE-RAGE Signaling in Enteric Glia to Prevent Neuro
Score: 0.61

Related Analyses (3)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Cell type vulnerability in Alzheimers Disease (SEA-AD transc
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

Packard Center for ALS Research
institution · KG edge: activates
MAP1LC3B — LC3B
gene · KG edge: associated_with
GPX4 Gene - Glutathione Peroxidase 4
gene · KG edge: activates
GPT - Alanine Transaminase (ALT)
gene · KG edge: associated_with
FTH1 Gene — Ferritin Heavy Chain 1
gene · KG edge: associated_with

Knowledge Graph (12 edges)

GOT1 provides_data_for ds-83b31ef18d49
GOT1 associated_with SQSTM1
GOT1 associated_with GPT
GOT1 associated_with ELAVL1
GOT1 associated_with GPX4
GOT1 activates BECLIN1
GOT1 associated_with P62
GOT1 associated_with FTH1
GOT1 associated_with MAP1LC3B
GOT1 associated_with TGFB1

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