gene 1,559 words KG: ELAVL1 2026-03-28
kind:genesection:genestopic:alzheimerstopic:parkinsonstopic:als
Contents

ELAVL1 Gene

🧬 Gene Info
Gene SymbolELAVL1
Full NameELAVL1
Chromosome19p13.2
Protein TypeGene
Functionis a member of the ELAV (Embryonic Lethal Abnormal Vision) family of RNA-binding proteins.
Primary Expressionneurons throughout the central and peripheral nervous systems:
Subcellular Localizationand RNA binding activity[@lee2020]
Molecular Weight36 kDa
Amino Acids326 aa
Exons10
PathwaysAutophagy, Ferroptosis, Proteasome, Ubiquitin-Proteasome
NCBI Gene IDSearch NCBI
GeneCardsELAVL1
Human Protein AtlasELAVL1
Associated DiseasesCarcinoma, Hepatocellular Carcinoma, Tumor
InteractionsBECLIN1, BECN1, NSUN2, YBX1, ATF3, UBIQUITIN
KG Connections108 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph

Related Hypotheses (11)

Metabolic Switch Targeting for A1→A2 Repolarization
Score: 0.48
Metabolic Reprogramming via Microglial Glycolysis Inhibition
Score: 0.39
Arginine Methylation Enhancement Therapy
Score: 0.46
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
CYP46A1 Overexpression Gene Therapy
Score: 0.63

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (6)

Packard Center for ALS Research
institution · KG edge: activates
BECN1 Gene
gene · KG edge: activates
BECN1 Gene
gene · KG edge: activates
ATF3 Gene
gene · KG edge: activates
ACTB Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

ELAVL1 associated_with GPX4
ELAVL1 associated_with SLC7A11
ELAVL1 associated_with FTH1
ELAVL1 associated_with P62
ELAVL1 associated_with MAP1LC3A
ELAVL1 associated_with PTGS2
ELAVL1 associated_with NCOA4
ELAVL1 associated_with TP53
ELAVL1 associated_with BECN1
ELAVL1 activates BECLIN1