gene 668 words KG: IL22
Contents

IL22

🧬 Gene Info
Gene SymbolIL22
Chromosome12q13
Functionis a member of the IL-10 cytokine family, encoded by the IL22 gene located on chromosome 12q13 [1](https://www.
Primary Expressionthe CNS: - Astrocytes: Produce IL22 in response to inflammation - Neurons: Express IL22R in some regions - Microglia: Respond to IL22 sign
PathwaysJAK-STAT pathway, MAPK pathway, PI3K
Ensembl IDENSG00000127353
GeneCardsIL22
Human Protein AtlasIL22
Associated DiseasesAls
InteractionsCD4, IFNG, IL31, IL6R, INFLAMMATION, MMP12
KG Connections61 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (2)

Prefrontal sensory gating circuit restoration via PV interne
Score: 0.78
H7: Enteric Nervous System Alpha-Synuclein Propagation Block
Score: 0.62

Related Analyses (1)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (10)

Brain Connectivity-Targeted tACS Trial in Early AD
clinical · proposed · Score: 0.95
AD Amyloid-Resilient Phenotype Study — Why Some amyloid-Posi
clinical · proposed · Score: 0.40
AD Combination Therapy Trial: Anti-Aβ + Anti-Tau
clinical · proposed · Score: 0.40
Biomarker-Guided Sequential Therapy Selection in Alzheimer's
clinical · proposed · Score: 0.40
tACS Connectivity Trial in Early Alzheimer's
clinical · proposed · Score: 0.40

See Also (7)

Hippocampal CA1 Pyramidal Neurons
cell · KG edge: expressed_in
Genes
index · KG edge: expressed_in
CD4 Gene
gene · KG edge: activates
GAIN Gene - GABA-A Receptor Associated Protein Like 2
gene · KG edge: causes
IFNG Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

IFNG expressed_in IL22
S100A8 expressed_in IL22
CLDN1 expressed_in IL22
IL22 expressed_in IL31
IL22 expressed_in S100A9
GAIN causes IL22
STAT3 causes IL22
IL22 activates CD4
IL22 expressed_in CLDN1
IL22 expressed_in S100A8

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