IL6R

Understanding Entity Pages

This page aggregates everything SciDEX knows about IL6R: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

IL6R is a gene implicated in neurodegeneration research. Key relationships include: activates, associated with, therapeutic target. Associated with ALS, Als, Cancer. Connected to 55 entities in the SciDEX knowledge graph.

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graph TD
    IL6R["<b>IL6R</b>"]
    gp130["gp130"]
    IL6R -->|"activates"| gp130
    Stroke{"Stroke"}
    IL6R -->|"inhibits"| Stroke
    Cardiovascular{"Cardiovascular"}
    IL6R -->|"therapeutic target"| Cardiovascular
    Als{"Als"}
    IL6R -->|"inhibits"| Als
    Hepatitis{"Hepatitis"}
    IL6R -->|"associated with"| Hepatitis
    Ms{"Ms"}
    IL6R -->|"regulates"| Ms
    Pneumonia{"Pneumonia"}
    IL6R -->|"associated with"| Pneumonia
    Cancer{"Cancer"}
    IL6R -->|"associated with"| Cancer
    Carcinoma{"Carcinoma"}
    IL6R -->|"associated with"| Carcinoma
    IL6R -->|"therapeutic target"| Ms
    ALS{"ALS"}
    IL6R -->|"inhibits"| ALS
    IL6R -->|"associated with"| Cardiovascular
    IL6["IL6"]
    IL6 -->|"interacts with"| IL6R
    proteases["proteases"]
    proteases -->|"catalyzes"| IL6R
    IL6 -->|"associated with"| IL6R
    IL6 -->|"activates"| IL6R
    GENES["GENES"]
    GENES -->|"activates"| IL6R
    HNF4A["HNF4A"]
    HNF4A -->|"activates"| IL6R
    PDGFRA["PDGFRA"]
    PDGFRA -->|"activates"| IL6R
    THBS2["THBS2"]
    THBS2 -->|"associated with"| IL6R
    MIRNAS["MIRNAS"]
    MIRNAS -->|"activates"| IL6R
    PI3K["PI3K"]
    PI3K -->|"associated with"| IL6R
    AKT["AKT"]
    AKT -->|"associated with"| IL6R
    CANCER["CANCER"]
    CANCER -->|"associated with"| IL6R
    style IL6R fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0