gene 720 words KG: IFNG 2026-03-23
kind:genesection:genesstate:published
Contents

IFNG Gene

🧬 Gene Info
Gene SymbolIFNG
Full NameIFNG
Protein TypeGene
FunctionIFN-γ is a homodimeric type II interferon that signals through the IFNGR1/IFNGR2 receptor complex.
PathwaysAkt, Wnt
NCBI Gene IDSearch NCBI
GeneCardsIFNG
Human Protein AtlasIFNG
Associated DiseasesALS, Alzheimer, Alzheimer's disease, Autoimmune, Inflammation
Known Drugs/CompoundsRAPAMYCIN, rapamycin
InteractionsLC3, RPTOR, RB1, EIF2AK3, RIPK1, MAPK14
KG Connections542 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph

Related Hypotheses (7)

Blocking AGE-RAGE Signaling in Enteric Glia to Prevent Neuro
Score: 0.42
CYP46A1 Overexpression Gene Therapy
Score: 0.63
APOE-Dependent Autophagy Restoration
Score: 0.61
Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.56
Age-Dependent Complement C4b Upregulation Drives Synaptic Vu
Score: 0.47

Related Analyses (5)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Gene expression changes in aging mouse brain predicting neur
neurodegeneration · archived

See Also (13)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: associated_with
Alzheimer Indonesia
institution · KG edge: associated_with
ATG5 — Autophagy Related 5
gene · KG edge: associated_with
ATG16L1 - Autophagy Related 16 Like 1
gene · KG edge: associated_with
ATG14 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

IFNG interacts_with LC3
IFNG interacts_with RPTOR
IFNG interacts_with RB1
IFNG interacts_with EIF2AK3
IFNG interacts_with RIPK1
IFNG interacts_with MAPK14
IFNG interacts_with BECN1
IFNG interacts_with ATF6
IFNG interacts_with DDIT3
IFNG interacts_with NBR1