gene 862 words KG: KCNH1 2026-03-22
kind:genesection:genesstate:published
Contents

KCNH1 Gene

🧬 Gene Info
Gene SymbolKCNH1
Full NamePotassium Voltage-Gated Channel Subfamily H Member 1
Chromosome1p36.33
Protein TypeChannel
Functionis a voltage-gated potassium channel with unique properties in neuronal excitability, cell proliferation, and synaptic transmission.
Amino Acids958 aa
UniProt IDQ14721
NCBI Gene ID3756
Ensembl IDENSG00000128408
OMIM603305
GeneCardsKCNH1
Human Protein AtlasKCNH1
ApproachTarget
KCNH1 blockersAntiepileptic
KCNH1 openersMemory enhancement
Associated Diseasesneurodegeneration
InteractionsNCAM1, RAB27A, COL4A1, CDKN2A, TLR4, TNC
KG Connections25 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (4)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.44
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.41

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Wnt Signaling in Neurodegeneration
mechanism · KG edge: inhibits
MAPK Signaling Pathways in Neurodegeneration
mechanism · KG edge: inhibits
Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: inhibits
WNT7A Gene
gene · KG edge: inhibits
TNC Gene
gene · KG edge: inhibits

Knowledge Graph (12 edges)

KCNH1 inhibits NCAM1
KCNH1 associated_with RGS1
KCNH1 inhibits RAB27A
KCNH1 inhibits COL4A1
KCNH1 inhibits Carcinoma
KCNH1 inhibits Ms
KCNH1 inhibits Cancer
KCNH1 inhibits Tumor
KCNH1 inhibits Apoptosis
KCNH1 inhibits Wnt