gene 3,796 words KG: FGF10 2026-03-26
kind:genesection:genestopic:alzheimerstopic:parkinsonsstate:published
Contents

FGF10 — Fibroblast Growth Factor 10

🧬 Gene Info
Gene SymbolFGF10
Full NameFibroblast Growth Factor 10
Chromosome5p12
Functionencodes a critical member of the fibroblast growth factor family that plays essential roles in embryonic development, tissue morphogenesis, and cellular proliferation.
Primary Expressionepithelial and neuronal tissues[@kumar1998]
Molecular Weight23.4 kDa
Amino Acids208 aa
UniProt IDO15520
NCBI Gene ID2255
Ensembl IDENSG00000164283
OMIM602115
GeneCardsFGF10
Human Protein AtlasFGF10
N-terminal signal peptideDirects secretion
FGF core domainConserved 120-amino acid core
Associated DiseasesAlzheimer's disease, Parkinson's disease
InteractionsDLC1, KCNH1, NCAM1, RGS1, RAB27A, COL4A1
KG Connections38 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (5)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.52
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.44
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.41

Related Analyses (3)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (6)

Cytochrome Therapeutics
clinical · proposed · Score: 0.46
Blood Biomarker vs Tau PET for Treatment Monitoring
clinical · proposed · Score: 0.46
cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.46
AAV-LRRK2 Gene Therapy IND-Enabling Study Design
clinical · proposed · Score: 0.46
Microbiome-Gut-Brain Axis in Alzheimer's Disease — mechanism
clinical · proposed · Score: 0.46

See Also (13)

MAPK Signaling Pathways in Neurodegeneration
mechanism · KG edge: inhibits
Fibroblast Growth Factor Signaling in Neurodegeneration
mechanism · KG edge: associated_with
Packard Center for ALS Research
institution · KG edge: inhibits
RGS1 — Regulator of G Protein Signaling 1
gene · KG edge: inhibits
RAB27A Gene
gene · KG edge: inhibits

Knowledge Graph (12 edges)

FGF10 inhibits DLC1
FGF10 inhibits KCNH1
FGF10 inhibits NCAM1
FGF10 inhibits RGS1
FGF10 inhibits RAB27A
FGF10 inhibits COL4A1
FGF10 inhibits Carcinoma
FGF10 inhibits Ms
FGF10 inhibits Cancer
FGF10 inhibits Tumor