gene 764 words KG: LYN
Contents

LYN Gene

🧬 Gene Info
Gene SymbolLYN
Chromosome8q13.1.
Protein TypeReceptor
FunctionLYN encodes a member of the Src family of non-receptor tyrosine kinases (SFKs).
Primary Expressionhematopoietic cells and neuronal tissue[@ref]
Molecular Weight56 kDa
Amino Acids21 aa
PathwaysMAPK signaling, Oxidative Stress
Ensembl IDENSG00000101313
GeneCardsLYN
Human Protein AtlasLYN
N-terminal myristoylation sitefor membrane association
Unique domaindetermines isoform specificity (LYN has two isoforms: p56 and p59)
SH3 and SH2 domainsfor protein-protein interactions
Catalytic tyrosine kinase domainfor enzymatic activity
Associated Diseasescancer
InteractionsSRC, ULK1, AMPK, CD36, FYN, ADRB2
KG Connections30 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph