| Gene Symbol | GSK3B |
| Full Name | Glycogen Synthase Kinase 3 Beta |
| Aliases | GSK-3β, TPKII, Tau tubulin kinase (TTBK) |
| Chromosome | 3q13.33 |
| Protein Type | Serine/Threonine Kinase |
| Function | is a constitutively active serine/threonine kinase encoded by the GSK3B gene that plays central and multifaceted roles in cellular physiology[@woodgett1990]. |
| Primary Expression | Brain (highest), liver, muscle, kidney |
| Molecular Weight | ~47 kDa |
| Amino Acids | 420 aa |
| Exons | 12 |
| Pathways | Akt, Cholesterol, Mapk, Microrna, Nf-Kb |
| UniProt ID | P49841 |
| NCBI Gene ID | 2932 |
| OMIM | 605004 |
| GeneCards | GSK3B |
| Human Protein Atlas | GSK3B |
| Associated Diseases | ALS, ALZHEIMER'S DISEASE, APOPTOSIS, Aging, Alzheimer |
| Known Drugs/Compounds | RAPAMYCIN, Tideglusib, Ficus deltoidea, Sulforaphane, Vitamin B1, Vitamin B2 |
| Interactions | AKT, PTEN, MTOR, MAP1LC3B, LC3, ERN1 |
| KG Connections | 1104 knowledge graph edges |
| Databases | GeneCardsHPASTRING |