Contents

NOTCH3 — Notch Receptor 3

🧬 Gene Info

Gene Symbol	NOTCH3
Full Name	Notch Receptor 3
Aliases	Notch 3
Chromosome	19p13.12
Protein Type	Receptor
Function	is a single-pass transmembrane receptor belonging to the Notch family of signaling proteins (NOTCH1-4 in mammals).
Primary Expression	Vascular smooth muscle cells, Pericytes, some neurons
Molecular Weight	270 kDa
Amino Acids	321 aa
Pathways	NOTCH, Notch, Notch Signaling, Notch signaling
UniProt ID	Q9UM47
NCBI Gene ID	4854
Ensembl ID	ENSG00000074181
OMIM	600276
GeneCards	NOTCH3
Human Protein Atlas	NOTCH3
Associated Diseases	Als, Alzheimer's disease
Interactions	AHR, AND, ANGPT1, BACE1, CANCER, FLCN
KG Connections	95 knowledge graph edges
Databases	GeneCards HPA STRING

Knowledge Graph