gene 2,811 words KG: PILRA 2026-03-26
kind:genesection:genesstate:publishedtopic:alzheimerstopic:parkinsons
Contents

PILRA Gene

🧬 Gene Info
Gene SymbolPILRA
Full NamePaired Immunoglobulin-Like Type 2 Receptor Alpha
Chromosome7q22.1
Protein FamilyPaired immunoglobulin-like receptor family
Protein TypeReceptor
Functionis an inhibitory immune receptor expressed primarily on cells of the immune system.
Molecular Weight31 kDa
Amino Acids279 aa
Gene TypeProtein-coding
UniProt IDQ9YH5Q
NCBI Gene ID9317
Ensembl IDENSG00000137216
OMIM604866
GeneCardsPILRA
Human Protein AtlasPILRA
Associated DiseasesALS, Alzheimer, Alzheimer's disease, Atherosclerosis, Macular Degeneration
InteractionsZCWPW1, PILRB, SORL1, ABCA7, MAF, BIN1
KG Connections83 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (14)

TREM2-Dependent Microglial Senescence Transition
Score: 0.69
CYP46A1 Overexpression Gene Therapy
Score: 0.63
APOE-Dependent Autophagy Restoration
Score: 0.61
Senescent Microglia Resolution via Maresins-Senolytics Combi
Score: 0.55
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.52

Related Analyses (6)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

See Also (13)

Tau Protein
protein · KG edge: therapeutic_target
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: therapeutic_target
Packard Center for ALS Research
institution · KG edge: associated_with
Alzheimer Indonesia
institution · KG edge: associated_with
APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: associated_with

Knowledge Graph (12 edges)

PILRA provides_data_for ds-83b31ef18d49
PILRA therapeutic_target IDUA
PILRA therapeutic_target TAU
PILRA therapeutic_target GRN
PILRA associated_with ZCWPW1
PILRA associated_with MAF
PILRA associated_with ABCA7
PILRA associated_with TNF
PILRA interacts_with ZCWPW1
PILRA co_mentioned ZCWPW1