| Gene Symbol | PLCG1 |
| Full Name | Phospholipase C Gamma 1 |
| Aliases | Page for PLCG1 |
| Protein Family | Phospholipase C gamma family |
| Protein Type | Enzyme |
| Function | PLCG1 is a phospholipase C isoform activated by receptor tyrosine kinases (RTKs). |
| Molecular Weight | 148.5 kDa |
| Amino Acids | 1290 aa |
| Pathways | oncogenic pathway activation |
| UniProt ID | P19174 |
| GeneCards | PLCG1 |
| Human Protein Atlas | PLCG1 |
| X domain | Phosphorylase C-like phosphodiesterase core that catalyzes PIP2 hydrolysis |
| Y domain | Regulatory accessory domain required for catalytic activity |
| C2 domain | Calcium-dependent membrane targeting |
| Associated Diseases | neurodegeneration |
| Interactions | LAMP2A, AUTOPHAGY, RB1, EGFR, TP53 |
| KG Connections | 27 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |