gene 506 words KG: PRDX5
Contents

PRDX5 — Peroxiredoxin 5

🧬 Gene Info
Gene SymbolPRDX5
Full NamePeroxiredoxin 5
Chromosome10q26.3
Protein TypeEnzyme
FunctionPRDX5 possesses several distinctive features
Primary ExpressionBrain, Liver, Kidney, Heart, Skeletal Muscle
Subcellular Localization**: Exists in both the cytosol and mitochondria
PathwaysNF-κB
UniProt IDP30041
NCBI Gene ID25824
Ensembl IDENSG00000101236
OMIM608348
GeneCardsPRDX5
Human Protein AtlasPRDX5
Associated DiseasesAls, ALZHEIMER'S DISEASE
InteractionsAPP, CANCER, CRLS1, CYP2E1, EGF, GPX1
KG Connections66 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.83

Related Analyses (2)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (14)

Neuroinflammation PET Imaging in CBS/PSP
diagnostic · KG edge: regulates
Neurodegeneration
disease · KG edge: regulates
Epigenetic Clocks in Neurodegeneration — Causal Drivers
experiment · KG edge: regulates
Genes
index · KG edge: regulates
ABCA1 - ATP-Binding Cassette Transporter A1
gene · KG edge: regulates

Knowledge Graph (12 edges)

CALR associated_with PRDX5
S100A6 associated_with PRDX5
AKT expressed_in PRDX5
PRDX5 associated_with CTSD
EGF activates PRDX5
GABPB1 upregulates PRDX5
GPX1 interacts_with PRDX5
KEAP1 co_discussed PRDX5
NRF2 co_discussed PRDX5
PI3K co_discussed PRDX5

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