gene 1,225 words KG: RAB11 2026-03-27
kind:genesection:genesstate:published
Contents

RAB11A — Ras-Related Protein Rab-11A

🧬 Gene Info
Gene SymbolRAB11A
Full NameRAB11A, member RAS oncogene family
AliasesPage for RAB11A, Ras-Related Protein Rab-11A
Chromosome15q21.3
FunctionRAB11A functions in the recycling endosome compartment
Molecular Weight~24 kDa
Amino Acids216 aa
UniProt IDP62491
NCBI Gene ID8766
Ensembl IDENSG00000103740
OMIM609758
GeneCardsRAB11A
Human Protein AtlasRAB11A
Protein ClassRab GTPase
Associated DiseasesALS, Aging, Ftd, Neurodegeneration
InteractionsRAB5, C1Q, UBIQUITIN, APOE, C1Q/C3, COMPLEMENT
KG Connections238 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (15)

SASP-Mediated Complement Cascade Amplification
Score: 0.70
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59
Circadian-Synchronized Proteostasis Enhancement
Score: 0.58
Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu
Score: 0.57

Related Analyses (9)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived

See Also (6)

Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: associated_with
Packard Center for ALS Research
institution · KG edge: associated_with
Alzheimer Indonesia
institution · KG edge: regulates
BIN1 — Bridging Integrator 1
gene · KG edge: associated_with
BDNF Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

RAB11 therapeutic_target STX17
RAB11 inhibits RAB5
RAB11 therapeutic_target SNAP29
RAB11 therapeutic_target IGF2BP1
RAB11 therapeutic_target LONP1
RAB11 therapeutic_target BDNF
RAB11 therapeutic_target FUS
RAB11 inhibits C1Q
RAB11 therapeutic_target AKT
RAB11 associated_with PI3K