gene 2,740 words KG: RAB2A 2026-03-26
kind:genesection:genesstate:published
Contents

RAB2A Gene

🧬 Gene Info
Gene SymbolRAB2A
Full NameRAB GTPase 2A
Chromosome11p15.5
Functionis a critical small GTPase involved in intracellular vesicle trafficking, particularly within the endoplasmic reticulum (ER)-to-Golgi transport pathway and within Golgi compartments.
Subcellular Localizationmembranes and GDP-bound RAB2A being predominately cytosolic. This cycling is regulated by guanine nucleotide exchange fa
Molecular Weight21 kDa
Amino Acids185 aa
Pathwaysautophagy pathway, lipid trafficking, ubiquitin-proteasome
UniProt ID[P61019](https://www.uniprot.org/uniprot/P61019)
Ensembl IDENSG00000118890
OMIM614512
GeneCardsRAB2A
Human Protein AtlasRAB2A
Associated DiseasesALS, Ms
Known Drugs/Compoundsrapamycin
InteractionsGABARAPL1, MAP1LC3B, PRKN, LAMP2, GABARAP, DNM1L
KG Connections109 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph