gene 746 words KG: GABARAP 2026-03-24
kind:genesection:genesstate:published
Contents

GABARAP Gene

🧬 Gene Info
Gene SymbolGABARAP
Full NameGABA Type A Receptor Associated Protein
Chromosome17p13.1
FunctionGABARAP is a member of the ATG8 family (MAP1LC3/GABARAP family) with multiple cellular functions
Gene TypeProtein-coding (ATG8 family)
PathwaysAkt, Autophagy, Endocytosis, Er Stress, Lysosomal Degradation
UniProt IDO95166
NCBI Gene ID23710
Ensembl IDENSG00000138967
OMIM607418
GeneCardsGABARAP
Human Protein AtlasGABARAP
DiseaseInheritance
AgentTarget
Small molecule autophagy inducersATG proteins
Associated DiseasesALS, Alzheimer, Amyotrophic Lateral Sclerosis, Ataxia, Cancer
Known Drugs/Compoundsrapamycin
InteractionsERN1, STAT3, IFNG, LC3, RPTOR, RB1
KG Connections979 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (16)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Senescent Microglia Resolution via Maresins-Senolytics Combi
Score: 0.55
Phase-Separated Organelle Targeting
Score: 0.52
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.52
SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK
Score: 0.51

Related Analyses (9)

Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

See Also (10)

Packard Center for ALS Research
institution · KG edge: associated_with
Alzheimer Indonesia
institution · KG edge: regulates
APC Gene
gene · KG edge: interacts_with
AMBRA1 Gene
gene · KG edge: associated_with
Gene Page: ALS4 (SENATAXIN)
gene · KG edge: associated_with

Knowledge Graph (12 edges)

GABARAP phosphorylates GRB2
GABARAP phosphorylates HMGB1
GABARAP phosphorylates HSP70
GABARAP phosphorylates HSPA5
GABARAP phosphorylates IFNG
GABARAP phosphorylates JNK
GABARAP phosphorylates LRRK2
GABARAP phosphorylates MAP1LC3A
GABARAP phosphorylates MAPK14
GABARAP phosphorylates MAVS