gene 746 words KG: GABARAP
Contents

GABARAP Gene

🧬 Gene Info
Gene SymbolGABARAP
Full NameGABA Type A Receptor Associated Protein
Chromosome17p13.1
FunctionGABARAP is a member of the ATG8 family (MAP1LC3/GABARAP family) with multiple cellular functions
PathwaysAkt, Autophagy, Endocytosis, Er Stress, Lysosomal Degradation
UniProt IDO95166
NCBI Gene ID23710
Ensembl IDENSG00000138967
OMIM607418
GeneCardsGABARAP
Human Protein AtlasGABARAP
Associated DiseasesAls, Alzheimer, Amyotrophic Lateral Sclerosis, Ataxia, Cancer
Known Drugs/Compoundsrapamycin
InteractionsActin, AKT1, AKT1S1, AMBRA1, AMPK, AMYLOID
KG Connections966 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (16)

Senescent Microglia Resolution via Maresins-Senolytics Combi
Score: 0.79
CYP46A1 Overexpression Gene Therapy
Score: 0.77
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
APOE Isoform Expression Across Glial Subtypes
Score: 0.74
SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK
Score: 0.74
Phase-Separated Organelle Targeting
Score: 0.73
Stress Granule Phase Separation Modulators
Score: 0.72
Autophagosome Maturation Checkpoint Control
Score: 0.71
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
R-Loop Resolution Enhancement Therapy
Score: 0.68
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67
RNA Granule Nucleation Site Modulation
Score: 0.66
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.66
DNMT1-Targeting Antisense Oligonucleotide Reset
Score: 0.65
PINK1/Parkin-Independent Mitophagy Bypass for Enhanced Donor
Score: 0.53
Prohibitin-2 Mitochondrial Cross-Seeding Hub Disruption
Score: 0.47

Related Analyses (9)

Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived

See Also (10)

AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates
Apoptosis in Neurodegeneration
entity · KG edge: interacts_with
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: associated_with
ACTB Gene
gene · KG edge: associated_with
AKT1 Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

OPTN interacts_with GABARAP
CASP3 interacts_with GABARAP
AKT1 interacts_with GABARAP
CALCOCO2 interacts_with GABARAP
CGAS interacts_with GABARAP
CFTR interacts_with GABARAP
SQSTM1 interacts_with GABARAP
RPS6KB1 interacts_with GABARAP
GRB2 interacts_with GABARAP
RHEB interacts_with GABARAP

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.