gene 578 words KG: RGS2 2026-03-24
kind:genesection:genesstate:published
Contents

RGS2 Gene - Regulator of G Protein Signaling 2

🧬 Gene Info
Gene SymbolRGS2
Full NameRegulator of G Protein Signaling 2
AliasesPage for RGS2 Gene, Page for RGS2 Protein
Chromosome1q31.3
FunctionRGS2 is a key negative regulator of G protein signaling
Primary Expressionmany tissues:
Molecular Weight24 kDa
UniProt IDP41221
NCBI Gene ID5997
Ensembl IDENSG00000147251
OMIM600861
GeneCardsRGS2
Human Protein AtlasRGS2
Associated Diseasesneurodegeneration
InteractionsCDC42, RAB5, ARHGEF7, AUTOPHAGY, RAB7L1, RAC1
KG Connections27 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Purinergic Signaling Polarization Control
Score: 0.55
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42

Related Analyses (8)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived

See Also (13)

LRRK2 G2019S Transgenic Mouse Model
model · KG edge: interacts_with
MAPK Signaling Pathways in Neurodegeneration
mechanism · KG edge: interacts_with
RAC1 Gene
gene · KG edge: interacts_with
RAB7L1 (RAB7 Like 1)
gene · KG edge: interacts_with
RAB5A Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

RGS2 interacts_with CDC42
RGS2 interacts_with RAB5
RGS2 interacts_with ARHGEF7
RGS2 regulates FHL1
RGS2 interacts_with Parkinson
RGS2 interacts_with Ms
RGS2 interacts_with Autophagy
RGS2 interacts_with Mapk
RGS2 interacts_with AUTOPHAGY
RGS2 associated_with DNA