| Gene Symbol | CDC42 |
| Full Name | Cell Division Cycle 42 |
| Chromosome | 1p36.1 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 21 kDa |
| Amino Acids | 191 aa |
| Exons | 6 |
| Pathways | Proteasome, Ubiquitin-Proteasome |
| UniProt ID | [P60953](https://www.uniprot.org/uniprot/P60953) |
| Ensembl ID | ENSG00000158062 |
| GeneCards | CDC42 |
| Human Protein Atlas | CDC42 |
| GTP-Binding Domain | Five conserved motifs (GxxxxGKST, DxxG, TxxxGKST, xDxx, CAAX box) |
| Switch I Region | Residues 32-45, conformational change on GTP/GDP binding |
| Switch II Region | Residues 60-76, effector interaction site |
| Associated Diseases | Als, Alzheimer, Diabetes, Ferroptosis, Inflammation |
| Interactions | ACTB, ACTG1, Actin, ACVR1, AGING, AKT |
| KG Connections | 418 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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