gene 1,109 words KG: CDC42 2026-03-24
kind:genesection:genesstate:published
Contents

CDC42 Gene

🧬 Gene Info
Gene SymbolCDC42
Full NameCell Division Cycle 42
Chromosome1p36.1
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight21 kDa
Amino Acids191 aa
Exons6
PathwaysProteasome, Ubiquitin-Proteasome
UniProt ID[P60953](https://www.uniprot.org/uniprot/P60953)
Ensembl IDENSG00000158062
GeneCardsCDC42
Human Protein AtlasCDC42
Associated DiseasesALS, Alzheimer, Diabetes, Ferroptosis, Inflammation
InteractionsATP5A1, SOD1, EGFR, RAB5, ACVR1, RGS2
KG Connections423 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (17)

Purinergic P2Y12 Inverse Agonist Therapy
Score: 0.48
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Senescent Microglia Resolution via Maresins-Senolytics Combi
Score: 0.55
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.52
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.52

Related Analyses (10)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

See Also (14)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: associated_with
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: activates
Alzheimer Indonesia
institution · KG edge: associated_with
APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: inhibits
ATP5A1 Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

CDC42 associated_with CASP3
CDC42 regulates SQSTM1
CDC42 regulates TUBB3
CDC42 regulates STK11
CDC42 regulates VIM
CDC42 associated_with BECN1
CDC42 regulates HDAC6
CDC42 associated_with GAPDH
CDC42 regulates MAP1LC3B
CDC42 regulates MAP3K5