Contents

DDB1 — DNA Damage Binding Protein 1

🧬 Gene Info

Gene Symbol	DDB1
Full Name	DNA Damage Binding Protein 1
Aliases	UV-DDB1, XPE-BF
Chromosome	11q12.2
Function	DNA damage recognition and repair, E3 ubiquitin ligase adapter
Molecular Weight	126.9 kDa
Amino Acids	1140
Exons	22
Pathways	Nucleotide excision repair, CUL4-DDB1 ubiquitin ligase
UniProt ID	Q16531
Ensembl ID	ENSG00000167986
GeneCards	DDB1
Human Protein Atlas	DDB1
CUL4A/CUL4B	Scaffold proteins that recruit the E2 conjugating enzyme
ROC1	RING finger protein that activates E2 enzymes
Associated Diseases	Cancer, Lung Cancer
Known Drugs/Compounds	rapamycin
Interactions	ACTB, AGING, AMBRA1, AMPK, AND, ANG
KG Connections	107 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Knowledge Graph