| Gene Symbol | TET1 |
| Full Name | TET1 |
| Chromosome | 10q21.3 |
| Protein Type | Gene |
| Function | Unlike passive demethylation (which occurs during DNA replication without maintenance of methylation marks), TET1-mediated demethylation is an active, enzyme-driven process |
| Primary Expression | embryonic stem cells and neural progenitor cells, and is essential for pluripotency and neurogenesis |
| Amino Acids | 2136 aa |
| Pathways | epigenetic regulation, neurotrophin signaling, unfolded protein response |
| UniProt ID | Q8NFU7 |
| NCBI Gene ID | 80312 |
| Ensembl ID | ENSG00000138336 |
| OMIM | 607042 |
| GeneCards | TET1 |
| Human Protein Atlas | TET1 |
| Associated Diseases | Rett Syndrome, Alzheimer Disease, Parkinson Disease, Intellectual Disability |
| Known Drugs/Compounds | Arsenic |
| Interactions | TET2, TET3, INFLAMMATION, DNA, GENES, BDNF |
| KG Connections | 32 knowledge graph edges |
| Databases | GeneCardsHPASTRING |