| Gene Symbol | TRKA |
| Chromosome | 1q23.1 |
| Protein Family | Trk family (TrkA, TrkB, TrkC) |
| Protein Type | Receptor |
| Function | is a high-affinity receptor tyrosine kinase for nerve growth factor (NGF), encoded by the NTRK1 gene on chromosome 1q21-22. |
| Primary Expression | basal forebrain cholinergic neurons (BFCNs), which are the primary source of acetylcholine to the hippocampus and neocortex |
| Molecular Weight | 140 kDa |
| Amino Acids | 796 aa |
| Exons | 17 |
| Pathways | PI3K |
| GeneCards | TRKA |
| Human Protein Atlas | TRKA |
| Pathway | Primary Effect |
| PI3K/Akt | Pro-survival, protein synthesis |
| Ras/ERK | Differentiation, gene transcription |
| Associated Diseases | Alzheimer, Alzheimer'S Disease, Pain, disease |
| Interactions | NRP1, NGF, GAIN, BDNF, TRKC, TRKB |
| KG Connections | 122 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |