gene 1,730 words KG: MELK
Contents

MELK Gene

🧬 Gene Info
Gene SymbolMELK
Full NameMaternal Embryonic Leucine Zipper Kinase
Chromosome9p13.2
Protein TypeKinase
Functionencodes a serine/threonine protein kinase of the AMPK-related kinase family.
Primary ExpressionEmbryonic stem cells, neural progenitors, some neurons, many cancers
Molecular Weight75 kDa
Amino Acids651 aa
Exons14
PathwaysAMPK
UniProt IDQ9Y2V2
NCBI Gene ID9833
Ensembl IDENSG00000165304
OMIM607025
GeneCardsMELK
Human Protein AtlasMELK
Associated DiseasesCancer, Colorectal Cancer, CRC, Inflammatory Bowel Disease, Tumor
Known Drugs/Compoundsrapamycin
InteractionsASC, ATG, BECLIN1, BECN1, BRG1, CCDC50
KG Connections137 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

MELK activates STAT3
MELK activates CD8
RIPK2 associated_with MELK
BECN1 associated_with MELK
TNFA associated_with MELK
STAT3 associated_with MELK
ASC associated_with MELK
PI3K associated_with MELK
BRG1 associated_with MELK
SQSTM1 associated_with MELK

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