| Gene Symbol | NLRP2 |
| Full Name | NLR Family Pyrin Domain Containing 2 |
| Chromosome | 19q13.42 |
| Protein Type | Receptor |
| Function | is a member of the NOD-like receptor (NLR) family that plays critical roles in innate immunity and inflammasome formation. |
| Primary Expression | neurons, astrocytes, and microglia, where it participates in t |
| Molecular Weight | 114 kDa |
| Amino Acids | 975 aa |
| Exons | 10 |
| Pathways | Inflammasome, Innate Immunity, pyroptosis |
| Ensembl ID | ENSG00000163352 |
| GeneCards | NLRP2 |
| Human Protein Atlas | NLRP2 |
| Phosphorylation | Kinases including PKR and CK2 can phosphorylate NLRP2 |
| Ubiquitination | NLRP2 is subject to both K63-linked and linear ubiquitination |
| Associated Diseases | Autoimmune |
| Interactions | AND, CARD8, GAIN, NEURODEGENERATIVE DISEASES, NLRP1, NLRP10 |
| KG Connections | 43 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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