NLRP1

Understanding Entity Pages

This page aggregates everything SciDEX knows about NLRP1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

NLRP1 is a protein involved in neurodegeneration research. Key relationships include: activates, expressed in, contributes to. Associated with Aging, Als, Alzheimer. Connected to 101 entities in the SciDEX knowledge graph.

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graph TD
    NLRP1["<b>NLRP1</b>"]
    Major_depressive_disorder{"Major depressive disorder"}
    NLRP1 -->|"associated with"| Major_depressive_disorder
    autophagy(["autophagy"])
    NLRP1 -->|"regulates"| autophagy
    pro_inflammatory_cytokines["pro-inflammatory cytokines"]
    NLRP1 -->|"activates"| pro_inflammatory_cytokines
    major_depressive_disorder{"major depressive disorder"}
    NLRP1 -->|"associated with"| major_depressive_disorder
    Ms{"Ms"}
    NLRP1 -->|"activates"| Ms
    Tumor{"Tumor"}
    NLRP1 -->|"inhibits"| Tumor
    Als{"Als"}
    NLRP1 -->|"expressed in"| Als
    Cancer{"Cancer"}
    NLRP1 -->|"inhibits"| Cancer
    NLRP1 -->|"interacts with"| Ms
    Carcinoma{"Carcinoma"}
    NLRP1 -->|"associated with"| Carcinoma
    NLRP1 -->|"regulates"| Als
    NLRP1 -->|"regulates"| Ms
    chronic_social_defeat_stress(["chronic social defeat stress"])
    chronic_social_defeat_stress -->|"activates"| NLRP1
    BAX["BAX"]
    BAX -->|"activates"| NLRP1
    PYROPTOSIS["PYROPTOSIS"]
    PYROPTOSIS -->|"regulates"| NLRP1
    HDAC6["HDAC6"]
    HDAC6 -->|"regulates"| NLRP1
    IFI16["IFI16"]
    IFI16 -->|"associated with"| NLRP1
    CARD8["CARD8"]
    CARD8 -->|"associated with"| NLRP1
    style NLRP1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0