gene 519 words KG: NRAS
Contents

NRAS Gene

🧬 Gene Info
Gene SymbolNRAS
Full NameNRAS Proto-Oncogene, GTPase
Chromosome1p13.2
FunctionNRAS is a member of the Ras family of small GTPases that cycles between active GTP-bound and inactive GDP-bound states.
Primary Expressionthe brain with high expression in the hippocampus, cortex, and cerebellum
Molecular Weight21.2 kDa
Amino Acids189 aa
PathwaysMAPK, PI3K, MAPK signaling
UniProt IDP01111
Ensembl IDENSG00000213281
GeneCardsNRAS
Human Protein AtlasNRAS
BrainNeurons, astrocytes, and microglia
SkinMelanocytes and keratinocytes
Immune SystemT cells, B cells, and myeloid cells
Associated DiseasesAls, Cancer, epilepsy, Ms
InteractionsAKT, AKT3, APC, BRAF, C1Q, CANCER
KG Connections162 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

C1Q activates NRAS
TNF activates NRAS
STAT1 activates NRAS
NRAS activates STAT1
NPM1 associated_with NRAS
TP53 associated_with NRAS
TET2 associated_with NRAS
DNMT3A associated_with NRAS
NRAS associated_with IDH1
NRAS associated_with IDH2

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