gene 2,967 words KG: PLAU
Contents

PLAU Gene (Urokinase)

🧬 Gene Info
Gene SymbolPLAU
AliasesuPA, urokinase, ATF
Chromosome10q22.2
Protein TypeProtease
Functionis a gene encoding a secreted serine protease that plays critical roles in fibrinolysis, extracellular matrix (ECM) remodeling, and cell migration.
Molecular Weight54 kDa
Amino Acids411 aa
Exons11
PathwaysTGF-β
UniProt IDP00750
NCBI Gene ID5328
GeneCardsPLAU
Human Protein AtlasPLAU
Associated DiseasesAls, Alzheimer, Leukemia, Ms
InteractionsACE, ACE2, ALZHEIMER, BACE1, Bdnf, BDNF
KG Connections173 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

FGF21 activates PLAU
APP biomarker_for PLAU
FNDC5 activates PLAU
S100B biomarker_for PLAU
PLAU activates CXCL10
PLAU biomarker_for C1Q
PLAU activates CX3CL1
PLAU activates VIM
PLAU activates BDNF
PLAU biomarker_for TGM2

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