gene 890 words KG: PPP1R15A
Contents

PPP1R15A Gene

🧬 Gene Info
Gene SymbolPPP1R15A
AliasesGADD34
Chromosome19q13
Protein TypeGene
Functionencodes a stress-inducible scaffold that recruits catalytic PP1 phosphatase to phospho-eIF2alpha substrates.
PathwaysBlood-Brain Barrier, Er Stress
GeneCardsPPP1R15A
Human Protein AtlasPPP1R15A
Associated Diseasesneurodegeneration
InteractionsAND, ATF4, CLDN5, CXCL1, CXCL2, CYTOKINES
KG Connections63 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

CXCL2 therapeutic_target PPP1R15A
IL6 therapeutic_target PPP1R15A
ATF4 activates PPP1R15A
PPP1R15A therapeutic_target IL12B
PPP1R15A activates XBP1
PPP1R15A therapeutic_target CXCL1
PPP1R15A activates DDIT3
PPP1R15A therapeutic_target CLDN5
PPP1R15A activates HSPA5
PPP1R15A therapeutic_target OCLN

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