protein 557 words KG: BECN1PROTEIN
Contents

Beclin-1 Protein

🔬 Protein Info
Gene SymbolBECN1PROTEIN
Full NameBeclin-1
Protein TypeProtein
Functionis a core autophagy scaffold protein encoded by BECN1.
UniProt IDSearch UniProt
GeneCardsBECN1PROTEIN
Human Protein AtlasBECN1PROTEIN
Associated DiseasesAD, ALI, Als, Alzheimer, Alzheimer's disease
Known Drugs/Compoundscrocin, HCQ, Isorhapontigenin, nicotine, rapamycin, RAPAMYCIN
InteractionsABCD3, ACAT1, ACETYL-COA, ACHE, ACOX1, ACTB
KG Connections3054 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

UniProtWikipedia

Related Hypotheses (10)

Transcriptional Autophagy-Lysosome Coupling
Score: 0.78
Autophagosome Maturation Checkpoint Control
Score: 0.71
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67
APOE-Dependent Autophagy Restoration
Score: 0.89
Circadian Clock-Autophagy Synchronization
Score: 0.76
Circadian-Synchronized Proteostasis Enhancement
Score: 0.74
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
Temporal Decoupling via Circadian Clock Reset
Score: 0.54

Related Analyses (7)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed

Related Experiments (2)

Autophagy Enhancement Drug Screening for Neurodegeneration
clinical · proposed · Score: 0.40
Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
Exosomal miR-155 in Neurodegeneration
biomarker · Pages share 3 hypotheses
Synaptic Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses
Liquid Biopsy in Neurodegeneration
biomarker · Pages share 3 hypotheses
Metabolomic Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses

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