| Gene Symbol | FYCO1 |
| Full Name | FYVE and Coiled-Coil Domain Containing 1 |
| Chromosome | 3p21.2 |
| Protein Family | Autophagy adaptor family |
| Function | FYCO1 encodes a autophagy adapter protein that links autophagosomes to the microtubule-based transport machinery. |
| Primary Expression | the lens, and mutations cause congenital cataract, often accompanying spastic paraplegia in SPG59 |
| Subcellular Localization | Autophagosomes, late endosomes, lysosomes |
| Molecular Weight | 1478 aa (~168 kDa) |
| Pathways | mTOR, mtor |
| UniProt ID | Q9BQR1 |
| NCBI Gene ID | 79443 |
| Ensembl ID | ENSG00000164120 |
| OMIM | 607781 |
| GeneCards | FYCO1 |
| Human Protein Atlas | FYCO1 |
| Associated Diseases | Cancer, Cardiovascular, Ischemia, Ms, Neurodegeneration, Parkinson |
| Known Drugs/Compounds | rapamycin |
| Interactions | TFEB, DR5, TRAIL, CASP8, TNF, BCL2 |
| KG Connections | 170 knowledge graph edges |
| Databases | GeneCardsHPASTRING |