protein 1,959 words KG: GSK3BPROTEIN 2026-03-27
kind:proteinsection:proteinsstate:published
Contents

GSK3B Protein (Glycogen Synthase Kinase 3 Beta)

🔬 Protein Info
Gene SymbolGSK3B
AliasesGSK-3β, TPKII, Tau tubulin kinase (TTBK)
Chromosome3q13.33
Protein TypeSerine/Threonine Kinase
Functionis a constitutively active serine/threonine kinase encoded by the GSK3B gene that plays central and multifaceted roles in cellular physiology[@woodgett1990].
Subcellular Localization</th><td>Cytoplasm, Nucleus, Mitochondria, Synapse</td></tr>
Molecular Weight47 kDa (420 amino acids)
Amino Acids420 aa
Exons12
PathwaysAkt, Cholesterol, Mapk, Microrna, Nf-Kb
GeneCardsGSK3B
Human Protein AtlasGSK3B
Associated DiseasesALS, ALZHEIMER'S DISEASE, APOPTOSIS, Aging, Alzheimer
Known Drugs/CompoundsRAPAMYCIN, Tideglusib, Ficus deltoidea, Sulforaphane, Vitamin B1, Vitamin B2
InteractionsAKT, PTEN, MTOR, MAP1LC3B, LC3, ERN1
KG Connections1104 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph