| Gene Symbol | POLD1 |
| Chromosome | 19q13.3 |
| Protein Family | DNA polymerase delta family |
| Function | The enzyme exhibits lower processivity compared to Pol ε (the leading strand polymerase) but achieves high fidelity through its intrinsic 3'→5' exonuclease proofreading activity[@burgers2019]. |
| Subcellular Localization | Nucleus |
| Molecular Weight | 124 kDa |
| UniProt ID | [P28340](https://www.uniprot.org/uniprot/P28340) |
| GeneCards | POLD1 |
| Human Protein Atlas | POLD1 |
| Associated Diseases | neurodegeneration |
| Interactions | POT1, MRE11, MUTYH, NBS1, WRN, ATM |
| KG Connections | 18 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |