gene 1,008 words KG: TREX1
Contents

TREX1 — Three Prime Repair Exonuclease 1

🧬 Gene Info
Gene SymbolTREX1
Full NameThree Prime Repair Exonuclease 1
Chromosome3p21.31
Functionis a gene located on chromosome 3p21.
Primary ExpressionUbiquitously expressed; high expression in brain, liver, spleen
Molecular Weight33.9 kDa
Amino Acids314 aa
Exons3
PathwaysNf-Κb
UniProt IDQ9NSW9
NCBI Gene ID9349
Ensembl IDENSG00000213465
OMIM607400
GeneCardsTREX1
Human Protein AtlasTREX1
Associated DiseasesInflammation
InteractionsAGING, AND, ARID1A, ATM, CANCER, CD8
KG Connections79 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38
PARP1 Inhibition Therapy
Score: 0.74
SIRT6-NAD+ Axis Enhancement Therapy
Score: 0.61
VCP-Mediated Autophagy Enhancement
Score: 0.59
Lysosomal Membrane Repair Enhancement
Score: 0.54

Related Analyses (3)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

ARID1A
gene · KG edge: activates
ATM Gene
gene · KG edge: interacts_with
CD8 Gene
gene · KG edge: activates
CGAS Gene
gene · KG edge: activates
CTC1 Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

SAMHD1 associated_with TREX1
TREX1 regulates IKBKG
TREX1 associated_with PSMB8
TREX1 activates CD8
TREX1 activates STING
TREX1 activates CGAS
TREX1 interacts_with VCP
TREX1 interacts_with NEIL1
TREX1 interacts_with POLD1
TREX1 interacts_with POT1

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