protein 660 words KG: TUBULIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

Tubulin Protein

🔬 Protein Info
Gene SymbolTUBULIN
Protein FamilyTubulin family
Functionis a protein encoded by the TUBB gene.
Subcellular LocalizationMicrotubules, cytoplasm
Molecular Weight55 kDa
Amino Acids4477 aa
PathwaysAutophagy, Phagocytosis, Proteasome, Ubiquitin-Proteasome
UniProt IDP07437
GeneCardsTUBULIN
Human Protein AtlasTUBULIN
Associated DiseasesAls, Amyotrophic Lateral Sclerosis, Ms, Pyroptosis
InteractionsJUN, ACTB, ATG7, TAU, ELAVL3, GFAP
KG Connections426 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (14)

Noradrenergic-Tau Propagation Blockade
Score: 0.51
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.48
Quantum Coherence Disruption in Cellular Communication
Score: 0.34
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.52
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51

Related Analyses (13)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived

Related Experiments (4)

Validation: Membrane-Nucleation in iPSC Neurons
validation · proposed · Score: 0.40
Proposed experiment from debate on Microglia activate astroc
falsification · proposed · Score: 0.40
s:** - Temporal analysis showing mitochondrial defects prece
falsification · proposed · Score: 0.40
Proposed experiment from debate on Microglia activate astroc
falsification · proposed · Score: 0.40

See Also (15)

Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: activates
Packard Center for ALS Research
institution · KG edge: causes
Alzheimer Indonesia
institution · KG edge: activates
ACTB Gene
gene · KG edge: activates
AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates

Knowledge Graph (12 edges)

TUBULIN associated_with P62
TUBULIN associated_with MAP3K5
TUBULIN associated_with UBIQUITIN
TUBULIN associated_with OCLN
TUBULIN regulates GJA1
TUBULIN associated_with SQSTM1
TUBULIN regulates CASP3
TUBULIN regulates GAPDH
TUBULIN regulates ACTB
TUBULIN associated_with TUBB3