| Gene Symbol | RXRA |
| Aliases | PPAR, RAR, VDR, TR |
| Chromosome | 9q34.3 |
| Protein Type | Receptor |
| Function | encodes a nuclear receptor that functions as a central integrator of multiple signaling pathways. |
| Molecular Weight | 50 kDa |
| Amino Acids | 462 aa |
| Exons | 10 |
| Pathways | Akt, Mapk, Sphingolipid |
| Ensembl ID | ENSG00000149257 |
| GeneCards | RXRA |
| Human Protein Atlas | RXRA |
| N-terminal activation domain (AF-1) | Variable region conferring tissue-specific activation |
| DNA-binding domain (DBD) | Two zinc fingers recognizing X-response elements (XREs) |
| Hinge region | Flexible connector with nuclear localization signals |
| Associated Diseases | neurodegeneration |
| Interactions | AGING, AKT, AKT1, APOE, HSP90AA1, MDM2 |
| KG Connections | 53 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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