Contents

RXRA

🧬 Gene Info

Gene Symbol	RXRA
Aliases	PPAR, RAR, VDR, TR
Chromosome	9q34.3
Protein Type	Receptor
Function	encodes a nuclear receptor that functions as a central integrator of multiple signaling pathways.
Molecular Weight	50 kDa
Amino Acids	462 aa
Exons	10
Pathways	Akt, Mapk, Sphingolipid
Ensembl ID	ENSG00000149257
GeneCards	RXRA
Human Protein Atlas	RXRA
N-terminal activation domain (AF-1)	Variable region conferring tissue-specific activation
DNA-binding domain (DBD)	Two zinc fingers recognizing X-response elements (XREs)
Hinge region	Flexible connector with nuclear localization signals
Associated Diseases	neurodegeneration
Interactions	AGING, AKT, AKT1, AND, APOE, HSP90AA1
KG Connections	54 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Knowledge Graph