| Gene Symbol | DUSP10 |
| Protein Type | Phosphatase |
| Function | is a member of the dual-specificity phosphatase family that specifically dephosphorylates and inactivates both JNK (c-Jun N-terminal Kinase) and p38 MAPK pathways. |
| Amino Acids | 482 aa |
| Pathways | MAPK, MAPK pathway |
| Ensembl ID | ENSG00000143507 |
| GeneCards | DUSP10 |
| Human Protein Atlas | DUSP10 |
| N-terminal Non-catalytic Domain | Contains binding sites for MAPK substrates and regulators |
| Phosphatase Catalytic Domain | Contains the HCX5R active site motif essential for phosphatase activity |
| Nuclear Export Signal (NES) | Allows shuttling between nucleus and cytoplasm |
| Associated Diseases | Als, Alzheimer, Ms |
| Interactions | TAU, NEUROTOXICITY, ALZHEIMER'S DISEASE, P38, MIRNAS, APOPTOSIS |
| KG Connections | 39 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |