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IDH1 Gene - Isocitrate Dehydrogenase 1

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slug	genes-idh1
entity_type	gene
kg_node_id	IDH1

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Linked Artifacts (123)

mentions🧫IDH1 and IDH2 mutation sequencing in CNS and non-CNS tumors80%

mentions🧫Clinical outcome analysis based on IDH mutation status80%

related🧫IDH1 and IDH2 mutation sequencing in CNS and non-CNS tumors72%

related🧫Clinical outcome analysis based on IDH mutation status72%

related🧫Animal Model Comparison for Neurodegenerative Disease Therap70%

related🧫Endocannabinoid System Dysfunction Validation in Parkinson&#70%

related🧫Glymphatic-Circadian Axis Enhancement Therapy for Parkinson&70%

related🧫Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag70%

related🧫Neural Oscillation Dysfunction Validation in Parkinson'70%

related🧫Oligodendrocyte-Myelin Dysfunction Validation in Parkinson&#70%

related🧫Proteasome-Ubiquitin System Dysfunction Validation in Parkin70%

related🧫Protein Aggregation Kinetic Validation Results70%

related🧫Purinergic Signaling Dysfunction Validation in Parkinson70%

related🧫Regulated Necrosis Validation Study in Parkinson's Dise70%

related🧫Stress Granule Dysfunction Validation in Parkinson's Di70%

related🧫Experiment Validation: In vitro ThT Assay70%

related🧫Animal Model Comparison for Neurodegenerative Disease Therap70%

related🧫Endocannabinoid System Dysfunction Validation in Parkinson&#70%

related🧫Glymphatic-Circadian Axis Enhancement Therapy for Parkinson&70%

related🧫Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag70%

related🧫Neural Oscillation Dysfunction Validation in Parkinson'70%

related🧫Oligodendrocyte-Myelin Dysfunction Validation in Parkinson&#70%

related🧫Proteasome-Ubiquitin System Dysfunction Validation in Parkin70%

related🧫Protein Aggregation Kinetic Validation Results70%

related🧫Purinergic Signaling Dysfunction Validation in Parkinson70%

related🧫Regulated Necrosis Validation Study in Parkinson's Dise70%

related🧫Stress Granule Dysfunction Validation in Parkinson's Di70%

related🧫Experiment Validation: In vitro ThT Assay70%

see_also📖ATRX — Alpha Thalassemia/Mental Retardation Syndrome X-Linke60%

see_also📖BRAF — B-Raf Proto-Oncogene, Serine/Threonine Kinase60%

see_also📖CIC - Capicua Transcriptional Repressor60%

see_also📖fubp160%

see_also📖H3F3A — H3.3 Histone A60%

see_also📖PHF6 Gene60%

see_also📖nadph-oxidase-inhibitors60%

see_also📖Alpha-Synuclein Seed Kinetic Staging in Parkinson's Dis60%

see_also📖dopaminergic-vta-pd60%

see_also📖Dorsal Raphe Serotonergic Neurons in Parkinson's Diseas60%

see_also📖Globus Pallidus Internus in Parkinsons Disease60%

see_also📖Melanocytes in Parkinson Disease60%

see_also📖Nigrostriatal Dopamine Terminals in Parkinson's Disease60%

see_also📖Dopaminergic Substantia Nigra Neurons in Parkinson's Di60%

see_also📖Vulnerable Dopaminergic Neurons in Parkinson's Disease60%

see_also📖AB-1005 (REGENERATE-PD) GDNF Gene Therapy Trial60%

see_also📖ABBV-951 (foslevodopa/foscarbidopa) for Parkinson's Dis60%

see_also📖Apocynin for Parkinson's Disease60%

see_also📖Bacillus Subtilis for Parkinson Disease (NCT06487975)60%

see_also📖biib122-luma-lrrk2-inhibitor-pd60%

see_also📖CT1-DAP001 iPS Cell-derived Dopaminergic Progenitors for Par60%

see_also📖CVN424 Phase 3 ARISE Trial for Parkinson's Disease60%

see_also📖Intranasal Insulin and Glutathione for PD (NOSE-PD)60%

see_also📖NCT05565443: MR-Guided Focused Ultrasound + GCase for Parkin60%

see_also📖nct05266417-nose-pd60%

see_also📖nct06365190-rtms-pd60%

see_also📖NCT06487975: Bacillus Subtilis Gut Microbiome Intervention f60%

see_also📖Autologous Stem Cell-Derived Dopaminergic Neurons for Parkin60%

see_also📖Dyadic Mindfulness for PD Carers (NCT06821230)60%

see_also📖Amino Acid Supplement in Parkinson's Disease (NCT06954660%

see_also📖Vibrotactile Stimulation Walking Speed PD Trial60%

see_also📖Noradrenergic Arousal System Phase 3 PD Trial (NCT07316296)60%

see_also📖tDCS + Nordic Walking for Parkinson's Disease Motor Sym60%

see_also📖NouvNeu001 Cell Therapy for Parkinson's Disease60%

see_also📖PDE4 Inhibitor PD Trial60%

see_also📖Retigabine PD Trial60%

see_also📖Valacyclovir for HSV-1-Positive Parkinson's Disease60%

see_also📖NCT05881460: Vibrotactile Coordinated Reset for Parkinson&#x60%

see_also📖AMP-PD: Accelerating Medicines Partnership: Parkinson's60%

see_also📖Alpha-Synuclein SAA Kinetics Study — Biological Staging Back60%

see_also📖Alpha-Synuclein Aggregation Triggers — Sporadic PD Initiatio60%

see_also📖Alpha-Synuclein Spreading Mechanism — Prion-Like Propagation60%

see_also📖Combination Therapy Sequencing in Parkinson's Disease60%

see_also📖Selective Vulnerability of Dopaminergic Neurons — Mechanism 60%

see_also📖GLP-1 Agonist Responder Prediction Study — Precision Medicin60%

see_also📖Non-Motor Symptom Progression in Parkinson's Disease — 60%

see_also📖Synaptic Mitochondrial Resilience Enhancement for Parkinson&60%

see_also📖Accelerating Medicines Partnership for Alzheimer's Dise60%

see_also📖Accelerating Medicines Partnership for Parkinson's Dise60%

see_also📖Fibrinogen and αVβ3 Integrin in Alpha-Synuclein Pathology60%

see_also📖MLCS Quantification Methods in Parkinson's Disease Rese60%

see_also📖Pallido-Thalamocortical Motor Pathway in Parkinson's Di60%

see_also📖PDLIM7 Epigenetic Activation in Parkinson's Disease60%

see_also📖SAA and Imaging for Prodromal Parkinson's Disease Trial60%

see_also📖AI-Powered Movement Analysis for Parkinson's Disease60%

see_also📖Digital Biomarker Platforms for Parkinson's Disease60%

see_also📖Digital Therapeutics for Parkinson's Disease60%

see_also📖Wearable Sensors for Parkinson's Disease60%

see_also📖Adenosine A2A Receptor Antagonists60%

see_also📖CUE1 Non-Invasive Vibrotactile Device for Parkinson's D60%

see_also📖Neurorestore Therapies for Parkinson's Disease60%

see_also📖Synaptic Plasticity Therapeutics for Parkinson's Diseas60%

see_also📖MDM4 (MDMX)60%

see_also📖Astrocytes60%

see_also📖APOB Gene60%

see_also📖CALM1 — Calmodulin 160%

see_also📖KCNH2 — Potassium Voltage-Gated Channel Subfamily H Member 260%

see_also📖TEAD1 — TEA Domain Transcription Factor 160%

see_also📖CD33 Modulation Therapy for Neurodegeneration60%

see_also📖KDM4A - Lysine Specific Demethylase 4A60%

see_also📖KDM4B (Lysine Demethylase 4B)60%

see_also📖KDM4C60%

related🧪Noradrenergic-Tau Propagation Blockade55%

mentions🧪Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem50%

mentions🧪Nucleolar Stress Response Normalization50%

mentions🧪Arginine Methylation Enhancement Therapy50%

mentions🧪Temporal TET2-Mediated Hydroxymethylation Cycling50%

mentions🧪Epigenetic Memory Erasure via TET2 Activation50%

mentions🧪TET2-Mediated Demethylation Rejuvenation Therapy50%

mentions🧪CYP46A1 Overexpression Gene Therapy50%

mentions🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th50%

related🔬What are the mechanisms underlying selective vulnerability o50%

related🔬What are the mechanisms underlying neuroinflammation resolut50%

related🔬Investigate how lipid raft composition (cholesterol metaboli50%

related🔬What are the mechanisms underlying selective vulnerability o50%

related🔬What are the mechanisms underlying neuroinflammation resolut50%

related🔬Investigate how lipid raft composition (cholesterol metaboli50%

related🔬Analyze circuit-level changes in neurodegeneration using All50%

related🔬What are the mechanisms underlying rna binding protein dysre50%

related🔬What are the mechanisms underlying epigenetic clocks and bio50%

mentions🔬Analyze circuit-level changes in neurodegeneration using All40%

related🧪CYP46A1 Overexpression Gene Therapy40%

related🧪Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem40%

related🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th40%

mentions🔬What are the mechanisms underlying selective vulnerability o35%