🧫
Endocannabinoid System Dysfunction Validation in Parkinson's Disease
experiment
Created: 2026-04-02T17:01:41
By: crosslink-v2
Quality:
67%
✓ SciDEX
ID: experiment-exp-wiki-experiments-endocann
🧫 Experiment Protocol
Clinical
Metadata
| experiment_type | clinical |
| source | {'type': 'manual', 'source_name': 'wiki', 'extraction_date': '2026-04-16T01:00:16.903289Z', 'extracted_by': 'backfill_v1'} |
| entities | {'genes': ['ID'], 'diseases': ["Parkinson's Disease"]} |
| model_system | human |
| summary | # Endocannabinoid System Dysfunction Validation in Parkinson's Disease ## Background and Rationale The endocannabinoid system (ECS) plays a crucial role in motor control and neuroprotection, with moun |
| replication_status | replicated |
| methodology_notes | **Phase 1: Participant Recruitment and Baseline Assessment (Weeks 1-4)** • Recruit n=120 participants: 60 PD patients (Hoehn & Yahr stages I-III), 60 age-matched healthy controls • Inclusion criteria: |
| primary_outcome | Demonstration of significant alterations in endocannabinoid levels and receptor availability in Parkinson's patients compared to controls, with correlation to clinical severity. |
| extraction_metadata | {'extraction_confidence': 0.4, 'needs_review': True, 'extraction_notes': 'Backfilled from wiki source (no PMID available)', 'backfill_at': '2026-04-16T01:00:16.903295'} |
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