gene

adora1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about adora1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

40Connections
0Hypotheses
0Analyses
3Outgoing
13Incoming

No summary available yet. View on Wiki →

🧬 Gene Info
Gene SymbolADORA1
Full NameAdenosine A1 Receptor
Chromosome1q32.1
Functionencodes a 326-amino acid protein that is widely expressed throughout the central and peripheral nervous systems.
Amino Acids326 aa
PathwaysEpigenetic, Synaptic Plasticity
GeneCardsADORA1
Human Protein AtlasADORA1
Associated DiseasesAlzheimer's disease, Epilepsy
KG Connections3 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Wiki Pages (9)

Knowledge base pages for this entity

Adenosine Signaling in Neurodegeneration

mechanism · 2643 words

ADORA3 Gene

gene · 1758 words

RGS12 Protein

protein · 1680 words

Adenosine A1/A3 Receptor Modulator Therapy

therapeutic · 1624 words

ADORA1 Gene

gene · 1272 words

Pathway Diagram

graph TD
    ADORA1["ADORA1"]
    ADORA1 -->|"activates"| Als["Als"]
    ADORA1 -->|"activates"| Ms["Ms"]
    ADORA1 -->|"activates"| Alzheimer["Alzheimer"]
    ADORA1 -->|"expressed in"| ADORA3["ADORA3"]
    ADORA1 -->|"activates"| ALZHEIMER["ALZHEIMER"]
    ADORA1 -->|"activates"| TAU["TAU"]
    ADORA1 -->|"expressed in"| MAPT["MAPT"]
    ADORA1 -->|"activates"| MEF2C["MEF2C"]
    ASTROCYTE["ASTROCYTE"] -->|"activates"| ADORA1
    LCN2["LCN2"] -->|"activates"| ADORA1
    ALZHEIMER -->|"activates"| ADORA1
    MEF2C -->|"activates"| ADORA1
    MAPT -->|"expressed in"| ADORA1
    NEURODEGENERATIVE_DISEASES["NEURODEGENERATIVE DISEASES"] -->|"activates"| ADORA1
    TAU_PATHOLOGY["TAU PATHOLOGY"] -->|"activates"| ADORA1
    AND["AND"] -->|"expressed in"| ADORA1

Outgoing (27)

TargetRelationTypeStr
MAPTexpressed_ingene0.50
Neuronexpressed_incell_type0.50
NEURONSexpressed_inconcept0.50

Incoming (13)

SourceRelationTypeStr
Caffeineinhibitsdrug0.95
MAPTupregulatesgene0.90
adenosineactivatescompound0.90
MIR133Adownregulatesgene0.85
MEF2Cactivatesgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found