Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about BAICALEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | BAICALEIN |
| Key Genes/Proteins | BDNF, AMPK, CD274, TNF, BECN1 |
| Related Diseases | APOPTOSIS, LUNG CANCER, ALZHEIMER'S DISEASE, CANCER |
| Related Pathways | MTOR SIGNALING |
Knowledge base pages for this entity
graph TD
BAICALEIN["BAICALEIN"]
BAICALEIN -->|"inhibits"| MTOR["MTOR"]
BAICALEIN -->|"targets"| CD274["CD274"]
BAICALEIN -->|"inhibits"| Glutamine_mTOR_Metabolic_Pathw["Glutamine-mTOR Metabolic Pathway"]
BAICALEIN -->|"promotes"| Apoptosis["Apoptosis"]
BAICALEIN -->|"inhibits"| Glutamine_Mtor_Metabolic_Pathw["Glutamine-Mtor Metabolic Pathway"]
BAICALEIN -->|"suppresses"| Tumor_Growth["Tumor Growth"]
BAICALEIN -->|"suppresses"| Cell_Proliferation["Cell Proliferation"]
Scutellaria_Baicalensis_Georgi["Scutellaria Baicalensis Georgi"] -->|"involved_in"| BAICALEIN| Target | Relation | Type | Str |
|---|---|---|---|
| BDNF | activates | gene | 0.70 |
| CD274 | activates | gene | 0.65 |
| APOPTOSIS | activates | phenotype | 0.65 |
| LUNG CANCER | inhibits | disease | 0.65 |
| MTOR SIGNALING | inhibits | pathway | 0.65 |
| ALZHEIMER'S DISEASE | treats | disease | 0.65 |
| TNF | inhibits | gene | 0.65 |
| MICROGLIA | activates | cell_type | 0.65 |
| BECN1 | associated_with | gene | 0.50 |
| AMPK | associated_with | gene | 0.50 |
| BDNF | associated_with | gene | 0.50 |
| CD274 | associated_with | gene | 0.45 |
| CANCER | associated_with | disease | 0.45 |
| MTOR | associated_with | gene | 0.45 |
| ALZHEIMER | associated_with | disease | 0.45 |
| CX3CR1 | associated_with | gene | 0.45 |
| MICROGLIA | associated_with | cell_type | 0.45 |
| TNF | associated_with | gene | 0.45 |
| Source | Relation | Type | Str |
|---|---|---|---|
| AMPK | inhibits | gene | 0.70 |
| APOPTOSIS | inhibits | phenotype | 0.65 |
| LUNG CANCER | associated_with | disease | 0.45 |
| CELL PROLIFERATION | associated_with | phenotype | 0.45 |
| TUMOR GROWTH | associated_with | phenotype | 0.45 |
| MTOR SIGNALING | associated_with | pathway | 0.45 |
| MTOR PATHWAY | associated_with | pathway | 0.45 |
| ALZHEIMER'S DISEASE | associated_with | disease | 0.45 |
| NEUROINFLAMMATION | associated_with | phenotype | 0.45 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||