concept

DTX1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DTX1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

32Connections
0Hypotheses
0Analyses
21Outgoing
11Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameDTX1
Key Genes/ProteinsGENES, KLF2, PIEZO1, DTX3L, ORAI1, NOTCH1
Related PathwaysAngiogenesis, Notch

Wiki Pages (1)

Knowledge base pages for this entity

ORAI1 Gene

gene · 1242 words

Pathway Diagram

graph TD
    DTX1["DTX1"]
    DTX1 -->|"involved_in"| Lymphatic_Sprouting["Lymphatic Sprouting"]
    DTX1 -->|"regulates"| GENES["GENES"]
    DTX1 -->|"regulates"| KLF2["KLF2"]
    DTX1 -->|"regulates"| PIEZO1["PIEZO1"]
    DTX1 -->|"regulates"| DTX3L["DTX3L"]
    DTX1 -->|"regulates"| ORAI1["ORAI1"]
    DTX1 -->|"regulates"| NOTCH1["NOTCH1"]
    DTX1 -->|"activates"| Angiogenesis["Angiogenesis"]
    ORAI1 -->|"regulates"| DTX1
    KLF2 -->|"regulates"| DTX1
    NOTCH1 -->|"regulates"| DTX1
    PIEZO1 -->|"regulates"| DTX1
    DTX3L -->|"regulates"| DTX1
    GENES -->|"regulates"| DTX1
    UBIQUITIN["UBIQUITIN"] -->|"regulates"| DTX1
    AND["AND"] -->|"regulates"| DTX1

Outgoing (21)

TargetRelationTypeStr
Lymphatic Sproutinginvolved_inprocess0.85
GENESregulatesgene0.60
KLF2regulatesgene0.60
PIEZO1regulatesgene0.60
DTX3Lregulatesgene0.60

Incoming (11)

SourceRelationTypeStr
ORAI1regulatesgene0.66
KLF2regulatesgene0.60
NOTCH1regulatesgene0.60
PIEZO1regulatesgene0.60
DTX3Lregulatesgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found