gene

ELMO1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ELMO1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

12Connections

0Hypotheses

0Analyses

11Outgoing

1Incoming

0Experiments

0Debates

Summary

ELMO1 is a gene implicated in neurodegeneration research. Key relationships include: regulates, activates, associated with. Associated with Infection, Inflammation. Connected to 13 entities in the SciDEX knowledge graph.

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🧬 Gene Info

Gene Symbol	ELMO1
Full Name	Engulfment and Cell Motility 1
Aliases	Page for ELMO1, Page for ELMO1 Protein
Chromosome	7p14.3
Function	Apoptotic Cell Clearance: ELMO1 mediates the recognition and engulfment of apoptotic cells by phagocytes [2]
Primary Expression	Microglia, Macrophages, Brain, Immune cells
Molecular Weight	85 kDa
Pathways	Autophagy
UniProt ID	Q9Y6I4
NCBI Gene ID	2004
Ensembl ID	ENSG00000126603
OMIM	606520
GeneCards	ELMO1
Human Protein Atlas	ELMO1
Associated Diseases	Parkinson's Disease, Alzheimer's Disease, Amyotrophic Lateral Sclerosis
Interactions	AUTOPHAGY, LC3, LC3B
KG Connections	12 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: ELMO1 — AlphaFold Q9Y6I4 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

ELMO1 - Engulfment and Cell Motility 1

gene · 783 words

→

ELMO1 Protein - Engulfment and Cell Motility 1

protein · 727 words

→

Pathway Diagram

graph TD
    ELMO1["ELMO1"]
    Infection{"Infection"}
    ELMO1 -->|"regulates"| Infection
    Inflammation{"Inflammation"}
    ELMO1 -->|"regulates"| Inflammation
    LYSOSOME(["LYSOSOME"])
    ELMO1 -->|"associated_with"| LYSOSOME
    INFLAMMATION(["INFLAMMATION"])
    ELMO1 -->|"regulates"| INFLAMMATION
    LC3(["LC3"])
    ELMO1 -->|"activates"| LC3
    LC3B(["LC3B"])
    ELMO1 -->|"activates"| LC3B
    ATG5(["ATG5"])
    ATG5 -->|"regulates"| ELMO1
    style ELMO1 fill:#1a3a4a,stroke:#ce93d8,stroke-width:3px,color:#ce93d8

Outgoing (11)

Target	Relation	Type	Str
Infection	regulates	disease	0.65
Inflammation	regulates	disease	0.65
LC3B	activates	gene	0.60
PHAGOCYTOSIS	associated_with	gene	0.60
AUTOPHAGY	activates	gene	0.60
Autophagy	activates	pathway	0.60
LYSOSOME	associated_with	gene	0.60
Phagocytosis	associated_with	pathway	0.60
INFLAMMATION	regulates	gene	0.60
LC3	activates	gene	0.60
ULK1	regulates	gene	0.60

Incoming (1)

Source	Relation	Type	Str
ATG5	regulates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning ELMO1 in their description or question text

No additional research found