IL6ST

Understanding Entity Pages

This page aggregates everything SciDEX knows about IL6ST: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Page for IL6ST - Interleukin 6 Signal Transducer (gp130)

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graph TD
    IL6ST["<b>IL6ST</b>"]
    Ms{"Ms"}
    IL6ST -->|"therapeutic target"| Ms
    Carcinoma{"Carcinoma"}
    IL6ST -->|"interacts with"| Carcinoma
    Cancer{"Cancer"}
    IL6ST -->|"interacts with"| Cancer
    Tumor{"Tumor"}
    IL6ST -->|"interacts with"| Tumor
    Apoptosis(["Apoptosis"])
    IL6ST -->|"interacts with"| Apoptosis
    neurodegeneration["neurodegeneration"]
    IL6ST -->|"implicated in"| neurodegeneration
    __synuclein["alpha-synuclein"]
    __synuclein -->|"activates"| IL6ST
    IL6["IL6"]
    IL6 -->|"interacts with"| IL6ST
    CYTOKINES["CYTOKINES"]
    CYTOKINES -->|"interacts with"| IL6ST
    RAGE["RAGE"]
    RAGE -->|"therapeutic target"| IL6ST
    IL6R["IL6R"]
    IL6R -->|"interacts with"| IL6ST
    LRP1["LRP1"]
    LRP1 -->|"interacts with"| IL6ST
    NR3C1["NR3C1"]
    NR3C1 -->|"interacts with"| IL6ST
    GATA1["GATA1"]
    GATA1 -->|"interacts with"| IL6ST
    MYC["MYC"]
    MYC -->|"interacts with"| IL6ST
    CANCER["CANCER"]
    CANCER -->|"interacts with"| IL6ST
    APOPTOSIS["APOPTOSIS"]
    APOPTOSIS -->|"interacts with"| IL6ST
    CREBBP["CREBBP"]
    CREBBP -->|"interacts with"| IL6ST
    style IL6ST fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0